Jakavi 5 mg (ruxolitinib 5 mg) contains the active substance ruxolitinib. Jakavi is used to treat adult patients with an enlarged spleen or with symptoms related to myelofibrosis, a rare form of blood cancer.
How to take Jakavi 5 mg (ruxolitinib 5 mg)
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The dose of Jakavi depends on the patient’s blood cell count. Your doctor will measure the amount of blood cells in your body and find the best dose for you, particularly if you have liver or kidney problems.
– The recommended starting dose is 15 mg twice daily or 20 mg twice daily, depending on your blood cell count.
– The maximum dose is 25 mg twice daily.
Your doctor will always tell you exactly how many Jakavi 5 mg (ruxolitinib 5 mg) tablets to take. During the treatment your doctor may recommend a lower or higher dose to you if the results of blood tests show that this is necessary, if you have problems with your liver or kidneys, or if you also need treatment with certain other medicines. If you receive dialysis, take one single dose of Jakavi on dialysis days, after the dialysis has been completed. Your doctor will tell you how many tablets to take for each dose.
You should take Jakavi every day at the same time, either with or without food. You should continue taking Jakavi for as long as your doctor tells you to. This is a long-term treatment. Your doctor will regularly monitor your condition to make sure that the treatment is having the desired effect.
If you have questions about how long to take Jakavi 5 mg (ruxolitinib 5 mg), talk to your doctor or pharmacist. If you experience certain side effects (e.g. blood disorders), your doctor might need to change the amount of Jakavi you have to take or tell you to stop taking Jakavi 5 mg (ruxolitinib 5 mg) for a while.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. Most of the side effects of Jakavi 5 mg (ruxolitinib 5 mg) are mild to moderate and will generally disappear after a few days to a few weeks of treatment.
Tell your doctor immediately if you experience any of the following side effects.
Some are very common (may affect more than 1 in 10 people), some are common (may affect up to 1 in 10 people):
– any sign of bleeding in the brain, such as sudden altered level of consciousness, persistent headache, numbness, tingling, weakness or paralysis (common)
– any sign of bleeding in the stomach or intestine, such as passing black or bloodstained stools, or vomiting blood (common)
– unexpected bruising and/or bleeding, unusual tiredness, shortness of breath during exercise or at rest, unusually pale skin, or frequent infections (possible symptoms of blood disorders) (very common)
– painful skin rash with blisters (possible symptoms of shingles (herpes zoster)) (common) – fever, chills or other symptoms of infections (very common)
– low level of red blood cells (anaemia), low level of white blood cells (neutropenia) or low level of platelets (thrombocytopenia) (very common)
Other side effects with Jakavi 5 mg (ruxolitinib 5 mg)